Perindopril t-Butylamine Salt

Alternative_name

(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine salt, Perindopril tert-butylamine, Perindopril erbumine
Description

Perindopril is a potent, brain-permeable angiotensin-converting enzyme (ACE) inhibitor (IC₅₀ = 1.05 nM). Unlike the other ACE inhibitors, inhibits tumor growth in hepatocellular carcinoma cells due to suppression of VEGF levels; also suppresses angiotensin II production in vitro.
CAS Number

107133-36-8
Structure Available

Yes
Salt Form

No
Molecular Formula

C₁₉H₃₂N₂O5₅ · C₄H₁₁N
Molecular Weight

441.6
Cell Permeable

Yes
Purity

≥98% by HPLC
Solubilities

H₂O (10 mg/ml)
Handling

Protect from air and moisture
Tag Line

A potent angiotensin converting-Enzyme (ACE) inhibitor
Storage Condition

-20°C
Shipping Condition

gel pack
Shelf Life

36 months
MDL Number

MFCD02313824
PubChem CID

441313
PubChem CID Link
SMILES

CCCC(C(=O)OCC)NC(C)C(=O)N1C2CCCCC2CC1C(=O)O.CC(C)(C)N
InChi

InChI=1S/C19H32N2O5.C4H11N/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24;1-4(2,3)5/h12-16,20H,4-11H2,1-3H3,(H,23,24);5H2,1-3H3/t12-,13-,14-,15-,16-;/m0./s1
InChi Key

IYNMDWMQHSMDDE-MHXJNQAMSA-N
Data Sheet Link
MSDS Available

Yes