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Alternative_name
(S)-5-(3-(1-((2-hydroxyethyl)amino)-2,3-dihydro-1H- inden-4-yl)-1,2,4-oxadiazol-5-yl)-2-isopropoxybenzonitrile; RPC1063
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Description
Ozanimod (RPC1063) is an orally bioavailable agonist of the sphingosine-1-phosphate receptor subtypes 1 (S1P1) and 5 (S1P5). S1P receptors belong to the family of G-protein-coupled receptor which contains five subtypes, denoting S1P1-5. S1P receptors are involved in coronary artery caliber, endothelial integrity, cardiac function, and lymphocyte recirculation.
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CAS Number
1306760-87-1
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₂₃H₂₄N₄O₃
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Molecular Weight
404.46
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Cell Permeable
Yes
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Purity
≥98% by HPLC
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Solubilities
DMSO (>20 mg/ml)
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Handling
Protect from air and light
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Tag Line
Apotent agonist of the sphingosine-1-phosphate receptor subtypes 1 (S1P1) and 5 (S1P5).
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
36 months
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PubChem CID
52938427
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SMILES
CC(C)OC1=C(C=C(C=C1)C2=NC(=NO2)C3=C4CCC(C4=CC=C3)NCCO)C#N
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InChi
InChI=1S/C23H24N4O3/c1-14(2)29-21-9-6-15(12-16(21)13-24)23-26-22(27-30-23)19-5-3-4-18-17(19)7-8-20(18)25-10-11-28/h3-6,9,12,14,20,25,28H,7-8,10-11H2,1-2H3/t20-/m0/s1
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InChi Key
XRVDGNKRPOAQTN-FQEVSTJZSA-N
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MSDS Available
Yes