Orlistat

• Catalog number
  B1020-250
• Price
  Please ask
• Size
  250 mg

• Alternative_name
  N-Formyl-L-leucine (1S)-1-[[(2S, 3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester; Tetrahydrolipstatin
• Description
  Orlistat is a cell-permeable, selective, and competitive lipase inhibitor (IC₅₀ = 0.15 µM). Targets serine hydrolases in the nervous system, such as diacylglycerol lipase (DAGL), which is responsible for the conversion of DAG to 2-AG. Partially inhibits the hydrolysis of triglycerides and lowers the absorption of dietary fat, promoting weight loss. Promotes the sensitivity to TRAIL in cancer cells by ROS-mediated pathways. Displays antiobesity and antihypercholesterolemic activity in vivo.
• CAS Number
  96829-58-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₉H₅₃NO₅
• Molecular Weight
  495.73
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A selective, and competitive lipase inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD05662360
• PubChem CID
  3034010
• PubChem CID Link
• SMILES
  CCCCCCCCCCCC(CC1C(C(=O)O1)CCCCCC)OC(=O)C(CC(C)C)NC=O
• InChi
  InChI=1S/C29H53NO5/c1-5-7-9-11-12-13-14-15-16-18-24(34-29(33)26(30-22-31)20-23(3)4)21-27-25(28(32)35-27)19-17-10-8-6-2/h22-27H,5-21H2,1-4H3,(H,30,31)/t24-,25-,26-,27-/m0/s1
• InChi Key
  AHLBNYSZXLDEJQ-FWEHEUNISA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Orlistat  
• Short name
  Orlistat
• Alternative name
  Orlistat

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