Olaparib

• Catalog number
  1952-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  4-(3-(4-(cycloprppanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazine-1(2H)-one; ADZ-2281; KU-59436
• Description
  Cell-permeable. A highly potent and selective PARP-inhibitor with IC₅₀ values of 5 nM and 1 nM for PARP-1 and PARP-2, respectively. Olaparib displays standalone activity in BRCA-1 deficient breast cancer cells.
• CAS Number
  763113-22-0
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₄H₂₃FN₄O₃
• Molecular Weight
  434.46
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~33 mg/ml) or EtOH (~ 1.7 mg/ml)
• Handling
  Protect from light and air
• Tag Line
  A highly potent and selective PARP-inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  48 months
• MDL Number
  MFCD13185161
• PubChem CID
  23725625
• PubChem CID Link
• SMILES
  C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
• InChi
  InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26- 21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7, 9-12,14H2,(H,27,30)
• InChi Key
  FDLYAMZZIXQODN-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Olaparib  
• Short name
  Olaparib
• Alternative name
  Olaparib

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