Olaparib
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Catalog number1952-5
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Price150.85 USD
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Size5 mg
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Alternative_name4-(3-(4-(cycloprppanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazine-1(2H)-one; ADZ-2281; KU-59436
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DescriptionCell-permeable. A highly potent and selective PARP-inhibitor with IC₅₀ values of 5 nM and 1 nM for PARP-1 and PARP-2, respectively. Olaparib displays standalone activity in BRCA-1 deficient breast cancer cells.
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CAS Number763113-22-0
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₄H₂₃FN₄O₃
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Molecular Weight434.46
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (~33 mg/ml) or EtOH (~ 1.7 mg/ml)
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HandlingProtect from light and air
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Tag LineA highly potent and selective PARP-inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life48 months
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MDL NumberMFCD13185161
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PubChem CID23725625
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SMILESC1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
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InChiInChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26- 21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7, 9-12,14H2,(H,27,30)
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InChi KeyFDLYAMZZIXQODN-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameOlaparib
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Alternative nameOlaparib
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