NVP-AUY922
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Catalog number1591-1
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PricePlease ask
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Size1 mg
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Alternative_name5-(2,4-Dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
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DescriptionA Hsp90 inhibitor. NVP-AUY922 has excellent potency against Hsp90 in a fluorescence polarization binding assay with an IC₅₀ of 21 nmol/L against the β-isoform and of 13 nmol/L for the α-isoform.
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CAS Number747412-49-3
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₆H₃₁N₃O₆
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Molecular Weight465.54
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Cell PermeableYes
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Purity≥99%
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SolubilitiesDMSO (10 mM)
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HandlingProtect from light and moisture
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Tag LineA Hsp90 inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24months
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PubChem CID10096043
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SMILESCCNC(=O)C1=C(C(=C2C=C(C(=CC2=O)O)C(C)C)ON1)C3=CC=C(C=C3)CN4CCOCC4
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InChiInChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33- 12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,28, 30H,4,9-12,15H2,1-3H3,(H,27,32)/b25-20-
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InChi KeySWDZPNJZKUGIIH-QQTULTPQSA-N
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MSDS AvailableYes
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Gene target
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Short nameNVP-AUY922
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Alternative nameNVP-AUY922
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