NVP-AUY922

  • Catalog number
    1591-1
  • Price
    Please ask
  • Size
    1 mg
  • Alternative_name
    5-(2,4-Dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
  • Description
    A Hsp90 inhibitor. NVP-AUY922 has excellent potency against Hsp90 in a fluorescence polarization binding assay with an IC₅₀ of 21 nmol/L against the β-isoform and of 13 nmol/L for the α-isoform.
  • CAS Number
    747412-49-3
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₆H₃₁N₃O₆
  • Molecular Weight
    465.54
  • Cell Permeable
    Yes
  • Purity
    ≥99%
  • Solubilities
    DMSO (10 mM)
  • Handling
    Protect from light and moisture
  • Tag Line
    A Hsp90 inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24months
  • PubChem CID
    10096043
  • SMILES
    CCNC(=O)C1=C(C(=C2C=C(C(=CC2=O)O)C(C)C)ON1)C3=CC=C(C=C3)CN4CCOCC4
  • InChi
    InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33- 12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,28, 30H,4,9-12,15H2,1-3H3,(H,27,32)/b25-20-
  • InChi Key
    SWDZPNJZKUGIIH-QQTULTPQSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    NVP-AUY922
  • Alternative name
    NVP-AUY922
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