NSC 23766

• Catalog number
  1941-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine trihydrochloride
• Description
  A cell-permeable, reversible, and selective Rac1 inhibitor; inhibiting Rac1 activation by the Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam 1 (IC₅₀ = 50 μM) without affecting the closely related GTPases, Cdc42, and RhoA activation. NSC 23766 has been used to investigate the role of Rac1 in such diverse cellular functions as stem cell mobilization, epithelial cell migration, angiogenesis, leukemia cell migration and growth, etc.
• CAS Number
  733767-34-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₄H₃₅N₇.3HCl
• Molecular Weight
  530.97
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  Water (100 mM)
• Handling
  Protect from light and moisture
• Tag Line
  A potent Rac1 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  16759159
• PubChem CID Link
• SMILES
  CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C2)N=C(C=C3N)C)C.Cl.Cl.Cl
• InChi
  InChI=1S/C24H35N7.3ClH/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30- 24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22;;;/h10-11,13-16H,6-9, 12H2,1-5H3,(H2,25,26)(H2,27,28,29,30);3*1H
• InChi Key
  CPUHORIUXPQCHW-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  NSC   23766  
• Short name
  NSC 23766
• Alternative name
  NSC 23766

Similar products