Nitrofurantoin

• Catalog number
  B2698-1G
• Price
  Please ask
• Size
  1 g

• Alternative_name
  NSC 44150,NSC 2107,1-[[(5-nitro-2-furanyl)methylene]amino]-2,4-imidazolidinedione
• Description
  Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections. Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts on many targets at once. It prevents kidney and bladder infection in rats following bladder inoculation with clinical isolates of P. mirabilis. Nitrofurantoin also prevents alkalization of urine as well as calculi and abscess formation in a rat model of P. vulgaris urinary tract infection.
• CAS Number
  67-20-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₈H₆N₄O₅
• Molecular Weight
  238.16
• Cell Permeable
  1
• Purity
  ≥98%
• Solubilities
  ~15 mg/ml Ethanol, ~25 mg/ml DMSO
• Handling
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Tag Line
  A nitrofuran antibiotic
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD00003224
• PubChem CID
  6604200
• PubChem CID Link
• SMILES
  C1C(=O)NC(=O)N1N=CC2=CC=C(O2)[N+](=O)[O-]
• InChi
  InChI=1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)/b9-3+
• InChi Key
  NXFQHRVNIOXGAQ-YCRREMRBSA-N
• Data Sheet Link
• MSDS Available
  1

• Gene target
  Nitrofurantoin  
• Short name
  Nitrofurantoin
• Alternative name
  Nitrofurantoin

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