ML-35

Quantity:

Alternative_name

N-[(2,4-Dichlorophenyl)methyl]-4-(methanesulfonamido)benzamide
Description

ML-335 is a potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator with EC₅₀ of 14.3 and 5.2 uM, respectively.
CAS Number

825658-06-8
Structure Available

Yes
Salt Form

No
Molecular Formula

C₁₅H₁₄Cl₂N₂O₃S
Molecular Weight

373.25
Cell Permeable

Yes
Purity

≥98% by HPLC
Solubilities

DMSO
Handling

Protect from air and light
Tag Line

A potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator
Storage Condition

-20°C
Shipping Condition

gel pack
Shelf Life

36 months
PubChem CID

1243054
PubChem CID Link
SMILES

CS(=O)(=O)NC1=CC=C(C=C1)C(=O)NCC2=C(C=C(C=C2)Cl)Cl
InChi

InChI=1S/C15H14Cl2N2O3S/c1-23(21,22)19-13-6-3-10(4-7-13)15(20)18-9-11-2-5-12(16)8-14(11)17/h2-8,19H,9H2,1H3,(H,18,20)
InChi Key

RDFIQTZRJRVFHK-UHFFFAOYSA-N
Data Sheet Link
MSDS Available

Yes

Quantity:

Identity

HGNC:5738
Gene

IGKV1-35
Long gene name

immunoglobulin kappa variable 1-35 (pseudogene)
Synonyms gene name
- immunoglobulin kappa variable 1-35
- immunoglobulin kappa variable 1-35 pseudogene
GenBank acession
- X71890
Locus

2p11.2
Discovery year

2000-04-18
Entrez gene record

28932
RefSeq identity
- NG_000834
Classification
- Immunoglobulin kappa locus at 2p11.2
VEGA ID

OTTHUMG00000151681

Identity

HGNC:5928
Gene

IGLV7-35
Long gene name

immunoglobulin lambda variable 7-35 (pseudogene)
Synonyms gene name
- immunoglobulin lambda variable 7-35
- immunoglobulin lambda variable 7-35 pseudogene
GenBank acession
- Z73660
Locus

22q11.22
Discovery year

2000-05-08
Entrez gene record

28777
RefSeq identity
- NG_000002
Classification
- Immunoglobulin lambda locus at 22q11.2
VEGA ID

OTTHUMG00000151067