Menadione

  • Catalog number
    2747-500
  • Price
    Please ask
  • Size
    500 mg
  • Alternative_name
    2-Methyl-1,4-naphthoquinone, Vitamin K3
  • Description
    Menadione is an inhibitor of indoleamine2,3-dioxygenase (IDO) (IC₅₀ ~ 1 µM). It induces apoptosis via elevation of peroxide radical levels. Cytotoxic in various cell lines.
  • CAS Number
    58-27-5
  • Structure Available
    Y
  • Salt Form
    No
  • Molecular Formula
    C₁₁H₈O₂
  • Molecular Weight
    172.18
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (1 mg/ml) or 96% EtOH (~ 15 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    An IDO inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00001681
  • PubChem CID
    4055
  • SMILES
    CC1=CC(=O)C2=CC=CC=C2C1=O
  • InChi
    InChI=1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
  • InChi Key
    MJVAVZPDRWSRRC-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Gene symbol
    NQO2
  • Short name
    Menadione
  • Alternative name
    Menadione
Gene info
  • Identity
  • Gene
  • Long gene name
    N-ribosyldihydronicotinamide:quinone reductase 2
  • Synonyms gene
  • Synonyms gene name
    • NAD(P)H menadione oxidoreductase 2, dioxin-inducible
    • NAD(P)H quinone dehydrogenase 2
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1991-09-13
  • Entrez gene record
  • Pubmed identfication
  • VEGA ID
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