Menadione
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Catalog number2747-500
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PricePlease ask
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Size500 mg
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Alternative_name2-Methyl-1,4-naphthoquinone, Vitamin K3
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DescriptionMenadione is an inhibitor of indoleamine2,3-dioxygenase (IDO) (IC₅₀ ~ 1 µM). It induces apoptosis via elevation of peroxide radical levels. Cytotoxic in various cell lines.
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CAS Number58-27-5
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Structure AvailableY
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Salt FormNo
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Molecular FormulaC₁₁H₈O₂
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Molecular Weight172.18
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (1 mg/ml) or 96% EtOH (~ 15 mg/ml)
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HandlingProtect from air and light
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Tag LineAn IDO inhibitor
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Storage Condition-20°C
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Shipping ConditionGel Pack
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Shelf Life36 months
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MDL NumberMFCD00001681
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PubChem CID4055
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SMILESCC1=CC(=O)C2=CC=CC=C2C1=O
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InChiInChI=1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
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InChi KeyMJVAVZPDRWSRRC-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Gene symbolNQO2
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Short nameMenadione
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Alternative nameMenadione
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Gene info
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Identity
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Gene
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Long gene nameN-ribosyldihydronicotinamide:quinone reductase 2
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Synonyms gene
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Synonyms gene name
- NAD(P)H menadione oxidoreductase 2, dioxin-inducible
- NAD(P)H quinone dehydrogenase 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-09-13
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Entrez gene record
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Pubmed identfication
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VEGA ID