Lubiprostone

• Catalog number
  B1319-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  (11a,15R)-11,15-Epoxy-16,16-difluoro-15-hydroxy-9-oxo-prostan-1-oic acid, Ru 0211, Spi 0211
• Description
  Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1 that activates ClC-2 and CFTR chloride channels. It has been suggested that lubiprostone opens CFTR or both CFTR and ClC-2 through interactions with the prostaglandin receptor EP4.
• CAS Number
  136790-76-6
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₀H₃₂F₂O₅
• Molecular Weight
  390.46
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~20 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1 that activates ClC-2 and CFTR chloride channels.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  157920
• PubChem CID Link
• SMILES
  CCCCC(C1(CCC2C(O1)CC(=O)C2CCCCCCC(=O)O)O)(F)F
• InChi
  InChI=1S/C20H32F2O5/c1-2-3-11-19(21,22)20(26)12-10-15-14(16(23)13-17(15)27-20)8-6-4-5-7-9-18(24)25/h14-15,17,26H,2-13H2,1H3,(H,24,25)/t14-,15-,17-,20-/m1/s1
• InChi Key
  WGFOBBZOWHGYQH-MXHNKVEKSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Lubiprostone  
• Short name
  Lubiprostone
• Alternative name
  Lubiprostone

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