Licochalcone A

• Catalog number
  B1909-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  (2E)-3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one
• Description
  Licochalcone A is a natural chalcone isolated originally from roots and rhizomes of licorice (Glycyrrhiza spp.). It has anti-inflammatory properties, supporting its use as a skin lightening agent. Licochalcone A (10-50 µM) induces apoptosis and suppresses migration and invasion of cancer cells in vitro. Recently, Licochalcone A has been found to irreversibly inhibit CYP3A4 enzyme, a critical component of the cytochrome P450 (CYP) family.
• CAS Number
  58749-22-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₁H₂₂O₄
• Molecular Weight
  338.39
• Cell Permeable
  Yes
• Purity
  ≥98%
• Solubilities
  DMSO (~10 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  An anti-inflammatory agent and CYP3A4 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD01417903
• PubChem CID
  5318998
• PubChem CID Link
• SMILES
  CC(C)(C=C)C1=C(C=C(C(=C1)C=CC(=O)C2=CC=C(C=C2)O)OC)O
• InChi
  InChI=1S/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+
• InChi Key
  KAZSKMJFUPEHHW-DHZHZOJOSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Licochalcone  
• Short name
  Licochalcone A
• Alternative name
  Licochalcone A

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