Lamotrigine

• Catalog number
  B1234-50
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine
• Description
  Lamotrigine is an inhibitor of voltage-gated sodium channels (Nav), blocking human Nav1.2, Nav1.5, and Nav1.8 with IC₅₀ values of 10, 62, and 96 μM, respectively. Also blocks heterologously expressed and native α4β2 nAChRs with a similar affinity to Na+ channels. Lamotrigine acts as an anticonvulsant and has applications in many diseases that feature seizures, including epilepsy and autism spectrum disorder.
• CAS Number
  84057-84-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₉H₇Cl₂N₅
• Molecular Weight
  256.09
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>25 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  An inhibitor of voltage-gated sodium channels (Nav)
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD00865333
• PubChem CID
  3878
• PubChem CID Link
• SMILES
  C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N
• InChi
  InChI=1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)
• InChi Key
  PYZRQGJRPPTADH-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Lamotrigine  
• Short name
  Lamotrigine
• Alternative name
  Lamotrigine

Product images

Similar products