Ki 8751

• Catalog number
  2677-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N-(2,4-Difluorophenyl)-N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-fluorophenyl]urea
• Description
  Ki 8751 is a potent, selective inhibitor of VEGFR-2 tyrosine kinase (IC₅₀ = 0.9 nM). It is >40-fold selective for VEGFR2 than c-Kit, PDGFRα and FGFR-2, little activity to EGFR, HGFR and InsR.
• CAS Number
  228559-41-9
• Structure Available
  Y
• Salt Form
  No
• Molecular Formula
  C₂₄H₁₈F₃N₃O₄
• Molecular Weight
  469.41
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>40 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A selective VEGFR-2 tyrosine kinase inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD09971092
• PubChem CID
  11317348
• PubChem CID Link
• SMILES
  COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC(=C(C=C3)NC(=O)NC4=C(C=C(C=C4)F)F)F
• InChi
  InChI=1S/C24H18F3N3O4/c1-32-22-11-15-20(12-23(22)33-2)28-8-7-21(15)34-14-4-6-19(17(27)10-14)30-24(31)29-18-5-3-13(25)9-16(18)26/h3-12H,1-2H3,(H2,29,30,31)
• InChi Key
  LFKQSJNCVRGFCC-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  8751  
• Short name
  Ki 8751
• Alternative name
  Ki 8751

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