Ki 16425
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Catalog number9545-25
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PricePlease ask
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Size25 mg
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Alternative_name3-[[[4-[4-[[[1-(2-Chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]propanoic acid
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DescriptionKi 16425 is a LPA (Lysophosphatidic acid) receptor antagonist with selectivity for LPA1 and LPA3. It exhibits Ki values of 0.34, 6.5, and 0.93 µM for the human LPA1, LPA2, and LPA3 receptors, respectively, as determined by measuring inositol phosphate production in RH7777-transfected cells.
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CAS Number355025-24-0
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₃H₂₃ClN₂O₅S
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Molecular Weight474.96
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>30 mg/ml) or EtOH (>20 mg/ml)
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HandlingProtect from air and light
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Tag LineA LPA (Lysophosphatidic acid) receptor antagonist
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD06798341
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PubChem CID10367662
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SMILESCC1=NOC(=C1NC(=O)OC(C)C2=CC=CC=C2Cl)C3=CC=C(C=C3)CSCCC(=O)O
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InChiInChI=1S/C23H23ClN2O5S/c1-14-21(25-23(29)30-15(2)18-5-3-4-6-19(18)24)22(31-26-14)17-9-7-16(8-10-17)13-32-12-11-20(27)28/h3-10,15H,11-13H2,1-2H3,(H,25,29)(H,27,28)
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InChi KeyLLIFMNUXGDHTRO-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameKi 16425
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Alternative nameKi 16425
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