Ketoconazole

• Catalog number
  B2735-250
• Price
  Please ask
• Size
  250 mg

• Alternative_name
  Fungoral,1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
• Description
  Ketoconazole is a broad-spectrum triazole antifungal agent. It inhibits the fungal cytochrome P450 (CYP) isoform CYP51, also known as lanosterol 14α-demethylase, which arrests ergosterol biosynthesis at the fungal membrane. Ketoconazole also inhibits human CYP3A4 (IC50 = 0.54 µM). Formulations containing ketoconazole have been used in the treatment of fungal infections.
• CAS Number
  65277-42-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₆H₂₈Cl₂N₄O₄
• Molecular Weight
  531.43
• Cell Permeable
  1
• Purity
  ≥98%
• Solubilities
  ~ 2 mg/ml DMSO
• Handling
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Tag Line
  An antifungal agent
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD00058579
• PubChem CID
  456201
• PubChem CID Link
• SMILES
  CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
• InChi
  InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m0/s1
• InChi Key
  XMAYWYJOQHXEEK-OZXSUGGESA-N
• Data Sheet Link
• MSDS Available
  1

• Gene target
  Ketoconazole  
• Short name
  Ketoconazole
• Alternative name
  Ketoconazole

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