Irinotecan Hydrochloride
#
-
Catalog number1752-250
-
Price:
-
Size250 mg
-
-
Alternative_nameS)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo1H-pyrano[3’,4’:6,7]-indolizino[1,2-b]quinolin-9-yl-[1,4’bipiperidine]-1’-carboxylate, Hydrochloride
-
DescriptionAn anticancer agent. This is a prodrug that is converted by tissue carboxylesterase to 7-ethyl-10-hydroxycamptothecin (SN-38), a potent inhibitor of DNA topoisomerase I.
-
CAS Number100286-90-6
-
Structure AvailableYes
-
Salt FormNo
-
Molecular FormulaC₃₃H₃₈N₄O₆. HCl
-
Molecular Weight623.14
-
Cell PermeableYes
-
Purity≥98% by HPLC
-
SolubilitiesDMSO (50 mg/ml)
-
HandlingProtect from air and moisture
-
Tag LineA DNA topoisomerase I inhibitor
-
Storage Condition-20°C
-
Shipping Conditiongel pack
-
Shelf Life24 months
-
MDL NumberMFCD01862255
-
PubChem CID74990
-
SMILESCCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.Cl
-
InChiInChI=1S/C33H38N4O6.ClH/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2;/h8-9,16-17,20,41H,3-7,10-15,18-19H2, 1-2H3;1H/t33-;/m0./s1
-
InChi KeyGURKHSYORGJETM-WAQYZQTGSA-N
-
MSDS AvailableYes
-
Gene target
-
Short nameIrinotecan Hydrochloride
-
Alternative nameIrinotecan Hydrochloride
-