Hydroxyfasudil Hydrochloride

  • Catalog number
    B1559-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    5-(1, 4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one;hydrochloride; HA-1100 hydrochloride
  • Description
    Hydroxyfasudil is a metabolite of Fasudil (Cat. No. 1787), that acts as a potent Rho-kinase (ROCK) inhibitor [(IC₅₀ = 12 μM (ROCK1); 0.17 μM (ROCK2)]. Acts as a vasodilator.
  • CAS Number
    155558-32-0
  • Structure Available
    Yes
  • Molecular Formula
    C₁₄H₁₈ClN₃O₃S
  • Molecular Weight
    343.83
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    H₂O (>5 mg/ml)
  • Handling
    Protect from air and moisture
  • Tag Line
    A potent Rho Kinase (ROCK) inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD06411567
  • PubChem CID
    11371328
  • SMILES
    C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CNC3=O.Cl
  • InChi
    InChI=1S/C14H17N3O3S.ClH/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17;/h1,3-5,7,15H,2,6,8-10H2,(H,16,18);1H
  • InChi Key
    XWWFOUVDVJGNNG-UHFFFAOYSA-N
  • MSDS Available
    Yes
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