Hydroxyfasudil Hydrochloride
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Catalog numberB1559-25
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PricePlease ask
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Size25 mg
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Alternative_name5-(1, 4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one;hydrochloride; HA-1100 hydrochloride
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DescriptionHydroxyfasudil is a metabolite of Fasudil (Cat. No. 1787), that acts as a potent Rho-kinase (ROCK) inhibitor [(IC₅₀ = 12 μM (ROCK1); 0.17 μM (ROCK2)]. Acts as a vasodilator.
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CAS Number155558-32-0
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Structure AvailableYes
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Molecular FormulaC₁₄H₁₈ClN₃O₃S
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Molecular Weight343.83
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesH₂O (>5 mg/ml)
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HandlingProtect from air and moisture
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Tag LineA potent Rho Kinase (ROCK) inhibitor
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Storage Condition-20°C
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Shipping ConditionGel Pack
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Shelf Life36 months
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MDL NumberMFCD06411567
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PubChem CID11371328
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SMILESC1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CNC3=O.Cl
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InChiInChI=1S/C14H17N3O3S.ClH/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17;/h1,3-5,7,15H,2,6,8-10H2,(H,16,18);1H
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InChi KeyXWWFOUVDVJGNNG-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameHydroxyfasudil Hydrochloride
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Alternative nameHydroxyfasudil Hydrochloride
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