Human CellExp™LAG3 /CD223, human recombinant

  • Catalog number
    7278-10
  • Supplier
  • Price
    256.46 USD
  • Size
    10 ug
  • Synonyms
    LAG3, CD223, FDC
  • Alternative_names
    LAG3, CD223, FDC
  • Description
    A protein involved in lymphocyte activation
  • Recombinant
    Yes
  • Source
    HEK293 cells
  • Purity by SDS PAGE
    ≥95%
  • Assay
    SDS-PAGE
  • Molecular Weight
    47 kDa
  • Storage Temp
    -20°C
  • Shipping
    Gel Pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized
  • Physical form description
    Lyophilized from 0.22 um filtered PBS (pH 7.4) with 5% trehalose
  • Reconstitution Instructions
    Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4).
  • Background Information
    Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC. It belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. LAG3/CD223 is one of the inhibitory receptors by negatively regulating cellular proliferation, activation, and homeostasis of T cells. LAG3 can bind to HLA class-II antigens and is involved in lymphocyte activation and autoimmunity. There are now LAG3 targeted therapies both in the clinic and in preclinical development, emphasizing the broad interest in this inhibitory receptor.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    LAG3
  • Short name
    CellExp™LAG3 /CD223, recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Humans
  • Alternative name
    H. sapiens CellExp™lymphocyte-activation gene 3 /CD223, H. sapiens Rec.
  • Alternative technique
    rec
  • Alternative to gene target
    lymphocyte-activation gene 3, CD223, LAG3 and IDBG-14994 and ENSG00000089692 and 3902, MHC class II protein binding, Cell surfaces, Lag3 and IDBG-188462 and ENSMUSG00000030124 and 16768, BT.18959 and IDBG-640276 and ENSBTAG00000034295 and 515155
Gene info
  • Identity
  • Gene
  • Long gene name
    lymphocyte activating 3
  • Synonyms gene name
    • lymphocyte-activation gene 3
  • Synonyms
  • Locus
  • Discovery year
    1991-06-03
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin like domain containing
    • CD molecules
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note:The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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Human CellExp LAG3 CD223 human recombinant - Gentaur.com
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