Human CellExp™ PDGF-CC, Human Recombinant

  • Catalog number
  • Price
    Please ask
  • Size
    10 µg
  • Synonyms
    Platelet-derived growth factor C, PDGFCC; PDGF-CC, Fallotein, Spinal cord-derived growth factor, SCDGF, VEGF-E
  • Alternative_names
    Platelet-derived growth factor C, PDGFCC; PDGF-CC, Fallotein, Spinal cord-derived growth factor, SCDGF, VEGF-E
  • Description
    Potent mitogen for a variety of cell types
  • Recombinant
  • Source
    HEK 293 cells
  • Purity by SDS PAGE
  • Assay
    SDS - PAGE
  • Molecular Weight
    16 kDa (6×His tag at the C-terminus)
  • Storage Temp
  • Shipping
    Gel Pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized powder
  • Physical form description
  • Reconstitution Instructions
    Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Do not vortex.
  • Background Information
    PDGF-CC is a member of the platelet-derived growth factor (PDGF) family, which was originally identified as a serum growth factor for fibroblasts, smooth muscle cells and glia cells. The PDGF family consists of proteins derived from four genes (PDGF-A, -B, -C, and -D) that form four disulfide-linked homodimers (PDGF-AA, -BB, -CC, and -DD) and one heterodimer (PDGF-AB). These proteins regulate diverse cellular functions by binding to and inducing the homo- or hetero-dimerization of two receptor tyrosine kinases (PDGF R alpha and R beta). PDGF-CC is expressed in multiple embryonic and adult cell types and tissues. PDGF-CC is involved in pathogenesis of neurologic diseases, cancer and fibrosis. The PDGF-CC ligand has also been shown to be involved in tumor growth by paracrine signaling through PDGFRα in malignant melanoma and cervical carcinoma.
  • Amino acid sequence
    aa Val 235 – Gly 345
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
  • Gene target
  • Gene symbol
  • Short name
    CellExp™ PDGF-CC, Recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
  • Alternative name
    H. sapiens CellExp™ PDGF-CC, H. sapiens Rec.
  • Alternative technique
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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