Human CellExp™ NKp46 / NCR1 / CD335, Human Recombinant

• Catalog number
  P1483-10
• Price
  Please ask
• Size
  10 µg

• Synonyms
  NCR1, LY94, CD335, NK-p46, hNKp46
• Alternative_names
  NCR1, LY94, CD335, NK-p46, hNKp46
• Description
  Cytotoxicity-activating receptor contribute to the increased efficiency of activated NK cells to mediate tumor cell lysis
• Recombinant
  True
• Source
  HEK 293 cells
• Purity by SDS PAGE
  >90%
• Molecular Weight
  This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.3 kDa. The protein migrates as 36-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Storage Temp
  -20ºC
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized powder
• Physical form description
  Lyophilized
• Reconstitution Instructions
  Reconstitute in sterile deionized water to the desired protein concentration.
• Background Information
  Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
• Amino acid sequence
  Gln 22 - Asn 254
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   NKp46   NCR1   CD335  
• Gene symbol
  NCR1
• Short name
  CellExp™ NKp46 / NCR1 / CD335, Recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ NKp46 / natural cytotoxicity triggering receptor 1 / CD335, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  natural cytotoxicity triggering receptor 1, CD335 and LY94 and NK-p46 and NKP46, NCR1 and IDBG-69753 and ENSG00000189430 and 9437, receptor signaling protein activity, Plasma membranes, Ncr1 and IDBG-137680 and ENSMUSG00000062524 and 17086, NCR1 and IDBG-641998 and ENSBTAG00000045529 and 369024

Gene info

• Identity
  HGNC:6731
• Gene
  NCR1
• Long gene name
  natural cytotoxicity triggering receptor 1
• Synonyms gene
  • LY94
• Synonyms gene name
  • lymphocyte antigen 94 (mouse) homolog (activating NK-receptor; NK-p46)
• Synonyms
  • NK-p46
  • NKP46
  • CD335
• GenBank acession
  • AJ001383
• Locus
  19q13.42
• Discovery year
  1999-04-09
• Entrez gene record
  9437
• Pubmed identfication
  • 9730896
• Classification
  • Immunoglobulin like domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000183212

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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