Human CellExp™ GITR / TNFRSF18, Rhesus macaque recombinant

• Catalog number
  P1083-10
• Price
  Please ask
• Size
  10 µg

• Synonyms
  AITR, GITR, TNFRSF18, CD357
• Alternative_names
  AITR, GITR, TNFRSF18, CD357
• Description
  Tumor necrosis factor receptor superfamily member 18
• Recombinant
  Yes
• Source
  HEK 293 cells
• Purity by SDS PAGE
  >95%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1 EU/ug
• Molecular Weight
  41.3 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
• Reconstitution Instructions
  Reconstitute in sterile deionized water to a concentration of 50 ug/ml.
• Background Information
  Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants
• About
  Monkeys like rhesus's or the rhesus macaque (Macaca mulatta) are the most used apes in laboraty models.

• Gene target
  CellExp™   GITR   TNFRSF18   macaque  
• Gene symbol
  TNFRSF18
• Short name
  CellExp™ GITR / TNFRSF18, macaque recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans, Rhesuses
• Alternative name
  H. sapiens CellExp™ GITR / tumor necrosis factor receptor superfamily, member 18, Rhesus macaque Rec.
• Alternative technique
  rec
• Alternative to gene target
  tumor necrosis factor receptor superfamily, member 18, AITR and CD357 and GITR and GITR-D, TNFRSF18 and IDBG-84584 and ENSG00000186891 and 8784, protein binding, Extracellular, Tnfrsf18 and IDBG-208288 and ENSMUSG00000041954 and 21936, TNFRSF18 and IDBG-635325 and ENSBTAG00000015632 and 516256

Gene info

• Identity
  HGNC:11914
• Gene
  TNFRSF18
• Long gene name
  TNF receptor superfamily member 18
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 18
• Synonyms
  • AITR
  • GITR
  • CD357
• GenBank acession
  • AF125304
• Locus
  1p36.33
• Discovery year
  1998-12-04
• Entrez gene record
  8784
• Pubmed identfication
  • 9177197
  • 10037686
• RefSeq identity
  • NM_004195
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000001414

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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