Human CellExp™ CD19, Fc Tag, Rhesus macaque recombinant
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Catalog numberP1329-50
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Price:
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Size50 µg
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SynonymsCD19, B4, CVID3, MGC12804
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Alternative_namesCD19, B4, CVID3, MGC12804
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DescriptionB-lymphocyte antigen CD19
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RecombinantYes
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SourceHEK 293 cells
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Purity by SDS PAGE≥95%
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AssaySDS-PAGE
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Endotoxin Level< 1 EU/ug
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Molecular Weight56.7 kDa
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Storage Temp-20°C
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ShippingGel pack
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Shelf Life12 months
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AppearanceLyophilized
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Physical form descriptionLyophilized from 0.22 um filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Generally Mannitol or Trehalose is added as a protectant before lyophilization
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Reconstitution InstructionsReconstitute in sterile deionized water to a concentration of 50 ug/ml.
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Background InformationB-lymphocyte antigen CD19 (CD19) is also known as B-lymphocyte surface antigen B4, Differentiation antigen CD19 and T-cell surface antigen Leu-12, which is a single-pass type I membrane protein and contains two Ig-like C2-type (immunoglobulin-like) domains. CD19 forms a complex with CD21, CD81 and CD225 in the membrane of mature B cells. CD19 interacts with GRB2 and SOS when phosphorylated on Tyr-348 and/or Tyr-378. CD19 also interacts with PLCG2 when phosphorylated on Tyr-409. CD19 is an important pan B cell marker and co-stimulatory protein in humans and mice. CD19 is a hallmark differentiation antigen of the B cell lineage and positively regulates antigen receptor signal transduction in mature B cells. CD19 defines signaling thresholds for the Ag receptor as well as other cell surface receptors that regulate B lymphocyte selection, activation, and differentiation. Defects in CD19 are a cause of hypogammaglobulinemia.
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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AboutMonkeys like rhesus's or the rhesus macaque (Macaca mulatta) are the most used apes in laboraty models.
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Gene target
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Gene symbolCD19
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Short nameCellExp™ CD19, Fc Tag, macaque recombinant
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TechniqueRecombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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LabelFc Tag
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SpeciesHumans, Rhesuses
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Alternative nameH. sapiens CellExp™ CD19 molecule, fragment c detection labelled, Rhesus macaque Rec.
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Alternative techniquerec
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Alternative to gene targetCD19 molecule, B4 and CVID3, CD19 and IDBG-23791 and ENSG00000177455 and 930, protein binding, Cell surfaces, Cd19 and IDBG-209475 and ENSMUSG00000030724 and 12478, CD19 and IDBG-638894 and ENSBTAG00000032122 and
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Gene info
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Identity
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Gene
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Long gene nameCD19 molecule
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Synonyms gene name
- CD19 antigen
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Locus
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Discovery year1991-06-04
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Entrez gene record
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Classification
- CD molecules
- Immunoglobulin like domain containing
- Minor histocompatibility antigens
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data