Human CellExp™ CD177

• Catalog number
  P1604-50
• Price
  Please ask
• Size
  50 ug

• Synonyms
  HNA-2a, PRV-1, N B1, NB1 GP, NB1 glycoprotein, Polycythemia rubra vera protein 1, Human neutrophil alloantigen 2a
• Alternative_names
  HNA-2a, PRV-1, N B1, NB1 GP, NB1 glycoprotein, Polycythemia rubra vera protein 1, Human neutrophil alloantigen 2a
• Description
  A glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein
• Recombinant
  1
• Source
  HEK293 cells
• Purity by SDS PAGE
  > 97% by SDS-PAGE
• Endotoxin Level
  < 0.1 EU/ug of the protein as determined by LAL method
• Molecular Weight
  Recombinant human CD177 protein migrates as a band at 90-100 kDa in SDS-PAGE
• Storage Temp
  -70°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Lyophilized protein
• Reconstitution Instructions
  Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water
• Background Information
  CD177 is a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein. CD177 contains two UPAR/Ly6 domains. CD177 is highly expressed in normal bone marrow and weakly expressed in fetal liver. Neutrophil-specific CD177 is a heterophilic binding partner of PECAM-1 (platelet endothelial cell adhesion molecule-1). This interaction mediates neutrophil transmigration.
• Amino acid sequence
  The target protein is expressed with the sequence (Met1-Gly407) of human CD177 (Accession #NP_065139.2.) fused with a Fc, 6×His tag at the C-terminus
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  CellExp™   CD177  
• Gene symbol
  CD177
• Short name
  CellExp™ CD177
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ CD177 molecule
• Alternative to gene target
  CD177 molecule, CD177 and IDBG-55103 and ENSG00000204936 and 57126, Plasma membranes, Cd177 and IDBG-155436 and ENSMUSG00000052212 and 68891, BT.78171 and IDBG-638968 and ENSBTAG00000002976 and 616350

Gene info

• Identity
  HGNC:30072
• Gene
  CD177
• Long gene name
  CD177 molecule
• Synonyms gene name
  • CD177 antigen
• Synonyms
  • PRV1
  • HNA2A
  • NB1
• Synonyms name
  • polycythemia rubra vera 1
• GenBank acession
  • AF146747
• Locus
  19q13.31
• Discovery year
  2005-08-12
• Entrez gene record
  57126
• Pubmed identfication
  • 10753836
  • 5552408
• RefSeq identity
  • NM_020406
• Classification
  • CD molecules
  • LY6/PLAUR domain containing
• VEGA ID
  OTTHUMG00000185320

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