Human CellExp™ CD163, Human recombinant

• Catalog number
  9226-10
• Price
  Please ask
• Size
  10 µg

• Synonyms
  CD163, M130
• Alternative_names
  CD163, M130
• Description
  Scavenger receptor for the hemoglobin-haptoglobin complex
• Recombinant
  Yes
• Source
  HEK 293 cells
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Purity
  ≥95%
• Endotoxin Level
  < 1 EU/ug
• Molecular Weight
  This protein is fused with a 6× His tag at C-terminus and has a calculated MW of 110.4 kDa. The protein migrates as 135-140 kDa in SDS-PAGE due to glycosylation.
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.22 um filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.
• Reconstitution Instructions
  Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 ug/ml
• Background Information
  Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is also known as hemoglobin scavenger receptor, which is a scavenger receptor for the hemoglobin-haptoglobin complex. CD163 has also been shown to mark cells of monocyte/macrophage lineage. A soluble form of the receptor exists in plasma, commonly denoted sCD163. sCD163 is generated by ectodomain shedding of the membrane bound receptor. sCD163 is upregulated in a large range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage activation syndrome, Gaucher’s disease, sepsis, HIV infection, rheumatoid arthritis and Hodgkin Lymphoma.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   CD163  
• Gene symbol
  CD163
• Short name
  CellExp™ CD163, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ CD163 molecule, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  CD163 molecule, M130 and MM130, CD163 and IDBG-16292 and ENSG00000177575 and 9332, protein binding, Extracellular, Cd163 and IDBG-186721 and ENSMUSG00000008845 and 93671, CD163 and IDBG-639861 and ENSBTAG00000019669 and 533844

Gene info

• Identity
  HGNC:1631
• Gene
  CD163
• Long gene name
  CD163 molecule
• Synonyms gene name
  • CD163 antigen
• Synonyms
  • M130
  • MM130
  • SCARI1
• GenBank acession
  • Z22968
• Locus
  12p13.31
• Discovery year
  2000-01-18
• Entrez gene record
  9332
• Pubmed identfication
  • 10403791
  • 8370408
• RefSeq identity
  • NM_004244
  • NM_203416
• Classification
  • CD molecules
  • Scavenger receptors
  • Scavenger receptor cysteine rich domain containing
• VEGA ID
  OTTHUMG00000168353

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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