GSK-121 trifluoroacetate
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Catalog numberB1034-500
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PricePlease ask
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Size500 ug
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Alternative_name(3-amino-1-piperidinyl)[1-methyl-2-(1-methyl-1H-indol-2-yl)-1H-benzimidazol-5-yl]-methanone, 2,2,2-trifluoroacetate
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DescriptionGSK-121 is a novel protein arginine deiminase 4 (PAD4) inhibitor. GSK-121 was shown to inhibit the citrullination of PAD4 target proteins in a functional assay with an IC₅₀ value of 3.2 µM.
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CAS Number1652591-80-4
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₃H₂₅N₅O •CF₃COOH
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Molecular Weight501.5
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Cell PermeableYes
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Purity≥98%
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SolubilitiesDMSO (~30 mg/ml)
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HandlingProtect from air and moisture
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Tag LineA novel protein arginine deiminase 4 (PAD4) inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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SMILESO=C(N1CC(N)CCC1)C2=CC=C3N(C)C(C(N4C)=CC5=C4C=CC=C5)=NC3=C2.OC(C(F)(F)F)=O
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InChiInChI=1S/C23H25N5O.C2HF3O2/c1-26-19-8-4-3-6-15(19)13-21(26)22-25-18-12-16(9-10-20(18)27(22)2)23(29)28-11-5-7-17(24)14-28;3-2(4,5)1(6)7/h3-4,6,8-10,12-13,17H,5,7,11,14,24H2,1-2H3;(H,6,7)
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InChi KeyCUCLWQZRCAQPJM-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Gene symbolTPRKB, SNORD4A, RNVU1-15
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Short nameGSK-121 trifluoroacetate
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Alternative nameGSK-121 trifluoroacetate
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Gene info
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Identity
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Gene
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Long gene nameTP53RK binding protein
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-02-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- KEOPS complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 4A
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Synonyms gene
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Synonyms gene name
- RNA, U101A small nucleolar
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-12-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene nameRNA, variant U1 small nuclear 15
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Synonyms gene
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Synonyms gene name
- RNA, variant U1 small nuclear 16
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Synonyms
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Locus
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Discovery year2013-04-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Variant U1 small nuclear RNAs