Granzyme B Inhibitor Ac-IEPD-CHO
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Catalog number
1119-1
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Price
Please ask
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Size
1 mg
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Alternative_name
Ac-IEPD-CHO, Granzyme B Inhibitor
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Description
A synthetic peptide that inhibits Granzyme B.
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Structure Available
No
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Peptide sequence
Ac-Le-Glu-Pro-Asp-CHO
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Salt Form
No
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Molecular Formula
C₂₂H₃₄N₄O₉
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Molecular Weight
498.53
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Cell Permeable
No
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Purity
>95% by HPLC
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Solubilities
DMSO
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Handling
Protect from light and moisture
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Tag Line
A granzyme B inhibitor
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
12 months
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PubChem CID
16760476
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SMILES
CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)N1CCCC1C(=O)NC(CC(=O)O)C=O)NC(=O)C
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InChi
InChI=1S/C22H34N4O9/c1-12(2)9-16(23-13(3)28)20(33)25-15(6-7-18(29)30)22(35)26-8-4-5-17(26)21(34)24-14(11-27)10-19(31)32/h11-12,14-17H,4-10H2,1,3H3,(H,23,28)(H,24,34)(H,25,33)(H,29,30)(H,31,32)/t14-,15-,16-,17?/m0/s1
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InChi Key
SVDITSCGEQCTNV-RXMKTKRKSA-N
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MSDS Available
Yes
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Additional description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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