Fostriecin sodium

• Catalog number
  B1241-10
• Price
  Please ask
• Size
  10 ug

• Alternative_name
  (6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one sodium salt
• Description
  Fostriecin is a potent inhibitor of the serine/threonine protein phosphatases PP2A and PP4 with IC₅₀ value of 3.2 and 3 nM, respectively. It also displays weak inhibition of topoisomerase II having IC₅₀ of 40 μM and PP1 with IC₅₀ of 131 μM. Fostriecin has antitumor activity against a wide spectrum of tumor cells in vitro and excellent activity against P388 and L1210 leukemias in vivo.
• CAS Number
  87860-39-7
• Structure Available
  Yes
• Salt Form
  Yes
• Molecular Formula
  C₁₉H₂₆O₉PNa
• Molecular Weight
  452.37
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  Water(>30 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent inhibitor of the serine/threonine protein phosphatases PP2A and PP4
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  16759606
• PubChem CID Link
• SMILES
  CC(C=CC1CC=CC(=O)O1)(C(CC(C=CC=CC=CCO)O)OP(=O)(O)[O-])O.[Na+]
• InChi
  InChI=1S/C19H27O9P.Na/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20;/h2-8,10-12,15-17,20-21,23H,9,13-14H2,1H3,(H2,24,25,26);/q;+1/p-1/b3-2-,6-4+,8-5-,12-11+;/t15-,16+,17+,19+;/m0./s1
• InChi Key
  XBUIKNRVGYFSHL-IAVQPKKASA-M
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Fostriecin   sodium  
• Short name
  Fostriecin sodium
• Alternative name
  Fostriecin sodium

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