Foretinib

• Catalog number
  9476-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  N-​​[3-​​fluoro-​​4-​​[[6-​​methoxy-​​7-​​[3-​​(4-​​morpholinyl)​propoxy]​-​​4-​​quinolinyl]​oxy]​phenyl]​-​​N'-​​(4-​​fluorophenyl)​-​1,​​1-​​cyclopropanedicarbox​amide; XL-880; GSK1363089G
• Description
  Foretinib is an ATP-competitive multi-kinase inhibitor that suppresses the activity of hepatocyte growth factor (HGF) receptor c-MET and vascular endothelial growth factor receptor-2 (VEGFR-2). In addition, Foretinib suppresses angiogenesis and lymphangiogenesis by blocking VEGFR-2/3 and TIE-2 signaling
• CAS Number
  849217-64-7
• Structure Available
  Yes
• Molecular Formula
  C₃₄H₃₄F₂N₄O₆
• Molecular Weight
  632.65
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>50 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  An ATP-competitive multi-kinase inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel pack
• Shelf Life
  36 months
• PubChem CID
  42642645
• PubChem CID Link
• SMILES
  COC1=CC2=C(C=CN=C2C=C1OCCCN3CCOCC3)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F
• InChi
  InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)
• InChi Key
  CXQHYVUVSFXTMY-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Foretinib  
• Short name
  Foretinib
• Alternative name
  Foretinib

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