Fluvastatin sodium

Alternative_name

7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid, sodium salt
Description

Fluvastatin sodium is a potent and selective HMG-CoA reductase inhibitor. It also inhibits the human cytochrome P450 (CYP) isoform CYP2C9 (IC50 = 100 nM). Fluvastatin inhibits increases in serum cholesterol, triglycerides, phospholipids, and thiobarbituric acid-reactive substances (TBARS) levels, as well as vascular angiotensin converting enzyme (ACE) activity in rabbits fed a high-cholesterol diet.
CAS Number

93957-55-2
Structure Available

Yes
Molecular Formula

C₂₄H₂₅FNNaO₄
Molecular Weight

433.45
Cell Permeable

1
Purity

≥98%
Solubilities

>10 mg/ml (DMSO) in 0
Handling

Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Tag Line

A HMG-CoA reductase inhibitor
Storage Condition

-20ºC
Shipping Condition

Gel Pack
Shelf Life

36 months
MDL Number

MFCD08063391
PubChem CID

23663976
PubChem CID Link
SMILES

CC(C)N1C2=CC=CC=C2C(=C1C=CC(CC(CC(=O)[O-])O)O)C3=CC=C(C=C3)F.[Na+]
InChi

InChI=1S/C24H26FNO4.Na/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30;/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30);/q;+1/p-1/b12-11+;/t18-,19-;/m1./s1
InChi Key

ZGGHKIMDNBDHJB-NRFPMOEYSA-M
Data Sheet Link
MSDS Available

1