EZCell™ Protein Transport Inhibitor Cocktail (500X)
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Catalog number
K932-500
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Price
Please ask
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Size
500 ul
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Description
The EZCell™ Protein Transport Inhibitor Cocktail (500X) is a cocktail composed of of Brefeldin A and Monensin, formulated in DMSO. Useful in assays that require prevention of protein transport to the extracellular space is required. Addition of this cocktail to cells in culture inhibits the intracellular protein secretory/transport pathway resulting in the accumulation of secreted proteins in the lumen of the endoplasmic reticulum and in the Golgi apparatus. This accumulation can then be detected by intracellular staining and flow cytometric analysis or Western blotting.
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CAS Number
See under individual products
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Structure Available
See under individual products
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Molecular Formula
See under individual products
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Molecular Weight
See under individual products
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Handling
Protect from air and light
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Tag Line
A Protein Transport Inhibitor cocktail
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
24 months
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SMILES
N/A
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InChi
N/A
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InChi Key
N/A
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MSDS Available
Yes
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Additional description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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