Evacetrapib

• Catalog number
  2558-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  trans-4-[[(5S)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl](2-methyl-2H-tetrazol-5-yl)amino]-2,3,4,5-tetrahydro-7,9-dimethyl-1H-1-benzazepin-1-yl]methyl]- cyclohexanecarboxylic acid; LY2484595
• Description
  Evacetrapib is a potent, and selective CETP (cholesteryl ester transfer protein) inhibitor. It inhibits human recombinant CETP protein (IC₅₀ = 5.5 nM ) and CETP activity in human plasma (IC₅₀ = 36 nM) in vitro. Unlike Torcetrapib (Cat. No. 2420 & 2533), Evacetrapib does not induce aldosterone or cortisol biosynthesis.
• CAS Number
  1186486-62-3
• Structure Available
  Y
• Salt Form
  No
• Molecular Formula
  C₃₁H₃₆F₆N₆O₂
• Molecular Weight
  638.65
• Cell Permeable
  Yes
• Purity
  ≥95% by HPLC
• Solubilities
  DMSO (>10 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent and selective CETP inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel pack
• Shelf Life
  24 months
• PubChem CID
  49836058
• PubChem CID Link
• SMILES
  CC1=CC(=C2C(=C1)C(CCCN2CC3CCC(CC3)C(=O)O)N(CC4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F)C5=NN(N=N5)C)C
• InChi
  InChI=1S/C31H36F6N6O2/c1-18-11-19(2)27-25(12-18)26(5-4-10-42(27)16-20-6-8-22(9-7-20)28(44)45)43(29-38-40-41(3)39-29)17-21-13-23(30(32,33)34)15-24(14-21)31(35,36)37/h11-15,20,22,26H,4-10,16-17H2,1-3H3,(H,44,45)/t20?,22?,26-/m0/s1
• InChi Key
  IHIUGIVXARLYHP-UXNJHFGPSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Evacetrapib  
• Short name
  Evacetrapib
• Alternative name
  Evacetrapib

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