Eltrombopag

  • Catalog number
    9489-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid; SB-497115; SB-497115-GR
  • Description
    Eltrombopag is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily.
  • CAS Number
    496775-61-2
  • Structure Available
    Yes
  • Molecular Formula
    C₂₅H₂₂N₄O₄
  • Molecular Weight
    442.47
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A small-molecule, nonpeptide thrombopoietin receptor agonist
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel pack
  • Shelf Life
    36 months
  • PubChem CID
    25181561
  • SMILES
    CC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)NN=C3C=CC=C(C3=O)C4=CC(=CC=C4)C(=O)O)C
  • InChi
    InChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,27-28H,1-3H3,(H,32,33)/b26-21-
  • InChi Key
    TYEXNVNUZXJNBN-QLYXXIJNSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Eltrombopag
  • Alternative name
    Eltrombopag
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