Eltrombopag
-
Catalog number9489-25
-
PricePlease ask
-
Size25 mg
-
-
Alternative_name3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid; SB-497115; SB-497115-GR
-
DescriptionEltrombopag is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily.
-
CAS Number496775-61-2
-
Structure AvailableYes
-
Molecular FormulaC₂₅H₂₂N₄O₄
-
Molecular Weight442.47
-
Cell PermeableYes
-
Purity≥98% by HPLC
-
SolubilitiesDMSO
-
HandlingProtect from air and light
-
Tag LineA small-molecule, nonpeptide thrombopoietin receptor agonist
-
Storage Condition-20°C
-
Shipping ConditionGel pack
-
Shelf Life36 months
-
PubChem CID25181561
-
SMILESCC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)NN=C3C=CC=C(C3=O)C4=CC(=CC=C4)C(=O)O)C
-
InChiInChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,27-28H,1-3H3,(H,32,33)/b26-21-
-
InChi KeyTYEXNVNUZXJNBN-QLYXXIJNSA-N
-
MSDS AvailableYes
-
Gene target
-
Short nameEltrombopag
-
Alternative nameEltrombopag
-