Ebselen

• Catalog number
  2169-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  2-Phenyl-1,2-benzisoselenazol-3-(2H)-one
• Description
  An organo-selenium compound that displays potent antioxidant properties. Acts as a glutathione peroxidase (GPX) mimic as well as being an excellent scavenger of peroxynitrite. The glutathione peroxidase-like activity of ebselen inhibits cyclooxygenase (COX) and lipoxygenases at micromolar concentrations. Also acts as a histone-lysine demethylase (HKDM) inhibitor. Inhibits JARID1B protein with an IC₅₀ of 5.17 µM.
• CAS Number
  60940-34-3
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₃H₉NOSe
• Molecular Weight
  274.18
• Cell Permeable
  Yes
• Purity
  ≥99%
• Solubilities
  DMSO (~ 5 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A glutathione peroxidase (GPx) mimetic and a peroxynitrite scavenger
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24months
• MDL Number
  MFCD00210937
• PubChem CID
  3194
• PubChem CID Link
• SMILES
  C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2
• InChi
  InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
• InChi Key
  DYEFUKCXAQOFHX-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Ebselen  
• Short name
  Ebselen
• Alternative name
  Ebselen

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