Dutasteride

• Catalog number
  B2662-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  (5α,17β)-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-azaandrost-1-ene-17-carboxamide; GG-745; 17β-N-[2,5-Bis(trifluoromethyl)phenyl]carbamoyl-4-aza-5α-androst-1-en-3-one; GI-198745
• Description
  Dutasteride (GG745) is a potent inhibitor of both 5α-reductase isozymes (IC₅₀ = 6 nM 5-AR1; 7 nM 5-AR2). Dutasteride may possess off-target effects on the androgen receptor (AR) due to its structural similarity to DHT. Dutasteride blocks testosterone conversion to dihydrotestosterone, and is used clinically for treating benign prostatic hyperplasia (BPH).
• CAS Number
  164656-23-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₇H₃₀F₆N₂O₂
• Molecular Weight
  528.53
• Cell Permeable
  True
• Purity
  ≥98%
• Solubilities
  >30 mg/ml in DMSO
• Handling
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Tag Line
  A potent, dual inhibitor of 5α-reductase isoenzymes types 1 and 2
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD00937869
• PubChem CID
  6918296
• PubChem CID Link
• SMILES
  CC12CCC3C(C1CCC2C(=O)NC4=C(C=CC(=C4)C(F)(F)F)C(F)(F)F)CCC5C3(C=CC(=O)N5)C
• InChi
  InChI=1S/C27H30F6N2O2/c1-24-11-9-17-15(4-8-21-25(17,2)12-10-22(36)35-21)16(24)6-7-19(24)23(37)34-20-13-14(26(28,29)30)3-5-18(20)27(31,32)33/h3,5,10,12-13,15-17,19,21H,4,6-9,11H2,1-2H3,(H,34,37)(H,35,36)/t15-,16-,17-,19+,21+,24-,25+/m0/s1
• InChi Key
  JWJOTENAMICLJG-QWBYCMEYSA-N
• Data Sheet Link
• MSDS Available
  1

• Gene target
  Dutasteride  
• Short name
  Dutasteride
• Alternative name
  Dutasteride

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