DSM265

• Catalog number
  B2639-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  DSM-265; 2-(1,1-difluoroethyl)-5-methyl-N-(4-(pentafluoro-l6-sulfanyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
• Description
  DSM265 is a potent, selective and long duration dihydroorotate dehydrogenase (DHODH)) inhibitor (IC₅₀ = 8.9 nM). DSM265 is potential useful for the prevention and treatment of malaria. DSM265 is highly selective towards DHODH of the malaria parasite Plasmodium, efficacious against both blood and liver stages of P. falciparum, and active against drug-resistant parasite isolates.
• CAS Number
  1282041-94-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₄H₁₂F₇N₅S
• Molecular Weight
  415.33
• Cell Permeable
  True
• Purity
  ≥98% by HPLC
• Solubilities
  >45 mg/ml in DMSO
• Handling
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Tag Line
  A potent and selective dihydroorotate dehydrogenase (DHODH)) inhibitor
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• PubChem CID
  51347395
• PubChem CID Link
• SMILES
  CC1=NC2=NC(=NN2C(=C1)NC3=CC=C(C=C3)S(F)(F)(F)(F)F)C(C)(F)F
• InChi
  InChI=1S/C14H12F7N5S/c1-8-7-11(26-13(22-8)24-12(25-26)14(2,15)16)23-9-3-5-10(6-4-9)27(17,18,19,20)21/h3-7,23H,1-2H3
• InChi Key
  OIZSVTOIBNSVOS-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  False

• Gene target
  DSM265  
• Short name
  DSM265
• Alternative name
  DSM265

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