Droxinostat

• Catalog number
  9570-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide
• Description
  Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8 with IC₅₀ values of 16.9, 2.47 and 1.46 μM, respectively. Droxinostat sensitizes cells to apoptosis by decreasing c-FLIPL and c-FLIPS expression, reducing cell survival, and inducing apoptosis.
• CAS Number
  99873-43-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₁H₁₄ClNO₃
• Molecular Weight
  243.69
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>40 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A selective inhibitor of HDAC3, HDAC6, and HDAC8
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD01326592
• PubChem CID
  568416
• PubChem CID Link
• SMILES
  CC1=C(C=CC(=C1)Cl)OCCCC(=O)NO
• InChi
  InChI=1S/C11H14ClNO3/c1-8-7-9(12)4-5-10(8)16-6-2-3-11(14)13-15/h4-5,7,15H,2-3,6H2,1H3,(H,13,14)
• InChi Key
  JHSXDAWGLCZYSM-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Droxinostat  
• Short name
  Droxinostat
• Alternative name
  Droxinostat

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