Droxinostat
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Catalog number9570-25
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Price:
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Size25 mg
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Alternative_name4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide
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DescriptionDroxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8 with IC₅₀ values of 16.9, 2.47 and 1.46 μM, respectively. Droxinostat sensitizes cells to apoptosis by decreasing c-FLIPL and c-FLIPS expression, reducing cell survival, and inducing apoptosis.
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CAS Number99873-43-5
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₁H₁₄ClNO₃
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Molecular Weight243.69
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>40 mg/ml)
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HandlingProtect from air and light
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Tag LineA selective inhibitor of HDAC3, HDAC6, and HDAC8
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD01326592
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PubChem CID568416
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SMILESCC1=C(C=CC(=C1)Cl)OCCCC(=O)NO
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InChiInChI=1S/C11H14ClNO3/c1-8-7-9(12)4-5-10(8)16-6-2-3-11(14)13-15/h4-5,7,15H,2-3,6H2,1H3,(H,13,14)
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InChi KeyJHSXDAWGLCZYSM-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameDroxinostat
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Alternative nameDroxinostat
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