DiscoveryPak™ FLT3 Kinase Inhibitor Set

• Catalog number
  S241-5
• Price
  Please ask
• Size
  5 inhibitors

• Description
  A convenient set containing five (5) FLT3 kinase inhibitors. The five inhibitors are 5 mg of Crenolanib (Cat. No. 9679); 5 mg of Gilteritinib (Cat. No. B1294); 5 mg of KW-2449 hydrochloride (Cat. No. B1208); 5 mg of Quizartinib (Cat. No. 2008), and 5 mg of Tandutinib (Cat. No. 2024).
• CAS Number
  See under the individual products
• Structure Available
  See under the individual products
• Salt Form
  No
• Molecular Formula
  See under the individual products
• Molecular Weight
  See under the individual products
• Cell Permeable
  Yes
• Purity
  See under the individual products
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A FLT3 kinase inhibitors set
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• SMILES
  N/A
• InChi
  N/A
• InChi Key
  N/A
• Data Sheet Link
• MSDS Available
  Yes
• Additional description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  DiscoveryPak™   FLT3   Kinase   Inhibitor   Set  
• Gene symbol
  FLT3
• Short name
  DiscoveryPak™ FLT3 Kinase Inhibitor Set
• Alternative name
  DiscoveryPak™ fms-related tyrosine kinase 3 phosphorylation catalyst suppressor Set
• Alternative to gene target
  fms-related tyrosine kinase 3, CD135 and FLK-2 and FLK2 and STK1, FLT3 and IDBG-19891 and ENSG00000122025 and 2322, transferase activity, nuclei, Flt3 and IDBG-209045 and ENSMUSG00000042817 and 14255, BT.28173 and IDBG-630678 and ENSBTAG00000018572 and 512700
• Tissue
  set

Gene info

• Identity
  HGNC:3765
• Gene
  FLT3
• Long gene name
  fms related receptor tyrosine kinase 3
• Synonyms gene name
  • fms-related tyrosine kinase 3
  • fms related tyrosine kinase 3
• Synonyms
  • STK1
  • FLK2
  • CD135
• GenBank acession
  • U02687
• Locus
  13q12.2
• Discovery year
  1990-07-30
• Entrez gene record
  2322
• Pubmed identfication
  • 8394751
• Classification
  • Immunoglobulin like domain containing
  • Receptor tyrosine kinases
  • CD molecules
• VEGA ID
  OTTHUMG00000016646
• Locus Specific Databases
  • LRG_457

MeSH Data

• Name
  Micropore Filters
• Concept
  Scope note: A membrane or barrier with micrometer sized pores used for separation purification processes.
• Tree numbers
  • E05.196.454.403
  • E07.560
• Qualifiers
  parasitology, microbiology, ethics, virology, trends, veterinary, history, classification, economics, standards, supply & distribution, adverse effects, statistics & numerical data

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