Danoprevir

• Catalog number
  B2184-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  (2R,6S,13aS,14aR,16aS,Z)-6-((tert-butoxycarbonyl)amino)-14a-((cyclopropylsulfonyl)carbamoyl)-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-2-yl 4-fluoroisoindoline-2-carboxylate; RG7227,ITMN-191
• Description
  Danoprevir (R7227) is a potent and selective inhibitor of Hepatitis C Virus (HCV) NS3/4A protease, a chymotrypsin-like serine protease (IC₅₀ = 0.2 – 3.5 nM). Useful for the treatment of Hepatitis C infection.
• CAS Number
  850876-88-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₃₅H₄₆FN₅O₉S
• Molecular Weight
  731.83
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>30 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent and selective inhibitor of Hepatitis C Virus (HCV) NS3/4A protease
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  53487990
• PubChem CID Link
• SMILES
  CC(C)(C)OC(=O)NC1CCCCCC=CC2CC2(NC(=O)C3CC(CN3C1=O)OC(=O)N4CC5=C(C4)C(=CC=C5)F)C(=O)NS(=O)(=O)C6CC6
• InChi
  InChI=1S/C35H46FN5O9S/c1-34(2,3)50-32(45)37-27-13-8-6-4-5-7-11-22-17-35(22,31(44)39-51(47,48)24-14-15-24)38-29(42)28-16-23(19-41(28)30(27)43)49-33(46)40-18-21-10-9-12-26(36)25(21)20-40/h7,9-12,22-24,27-28H,4-6,8,13-20H2,1-3H3,(H,37,45)(H,38,42)(H,39,44)/b11-7+/t22-,23-,27+,28+,35-/m1/s1
• InChi Key
  ZVTDLPBHTSMEJZ-AIYSODCISA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Danoprevir  
• Short name
  Danoprevir
• Alternative name
  Danoprevir

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