CPTH2 (hydrochloride)

• Catalog number
  B2815-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  4-(4-chlorophenyl)-2-(2-cyclopentylidenehydrazinyl)thiazole hydrochloride, Histone Acetyltransferase Inhibitor IV, CPTH2
• Description
  CPTH2 (hydrochloride) is an inhibitor of Histone Acetyltransferase (HAT) activity of Gcn5. Gcn5 acetylates histones H2B and H3. CPTH2 inhibited HAT reaction in vitro and it decreased acetylation of histone H3 at the specific H3-K14 site at micromolar concentrations. CPTH2 inhibited the Gcn5p dependent network. CPTH2 reduced the growth of adenovirus by inhibiting the lysine acetyltransferase activity of Gcn5.
• CAS Number
  2108899-91-6
• Structure Available
  True
• Salt Form
  True
• Molecular Formula
  C₁₄H₁₅Cl₂N₃S
• Molecular Weight
  328.26
• Cell Permeable
  True
• Purity
  ≥95%
• Solubilities
  5 mg/ml in ethanol and DMF in 0, 16 mg/ml in in DMSO
• Handling
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Tag Line
  An inhibitor of Histone Acetyltransferase activity of Gcn5
• Storage Condition
  -20ºC
• Shipping Condition
  RT
• Shelf Life
  36 months
• SMILES
  ClC1=CC=C(C2=CSC(N/N=C3CCCC/3)=N2)C=C1.[H]Cl
• InChi
  InChI=1S/C14H14ClN3S.ClH/c15-11-7-5-10(6-8-11)13-9-19-14(16-13)18-17-12-3-1-2-4-12;/h5-9H,1-4H2,(H,16,18);1H
• InChi Key
  ODVWZAKKCNHATB-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  True

• Gene target
  CPTH2   hydrochloride  
• Short name
  CPTH2 (hydrochloride)
• Alternative name
  CPTH2 (hydrochloride)

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