Cathepsin L, human recombinant
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Catalog number1135-1000
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Price:
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Size1 mg
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SynonymsCathepsin
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Alternative_namesCathepsin L1, Major excreted protein, Cathepsin U, Cathepsin V
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DescriptionLysosomal cysteine protease involved in protein degradation, arthritis, apoptosis, and cancer
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RecombinantYes
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SourceE. coli
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Purity by SDS PAGE≥90%
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AssaySDS-PAGE
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Activity Specifications test method> 10000 mU/mg (1 U = digestion of 1 µmole of Z-Phe-Arg-AFC substrate (K142-100) per minute at 37°C in 50 mM Sodium Acetate, 100 mM NaCl, pH 5.5).
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Biological activity> 10000 mU/mg (1 U = digestion of 1 µmole of Z-Phe-Arg-AFC substrate (K142-100) per minute at 37°C in 50 mM Sodium Acetate, 100 mM NaCl, pH 5.5).
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Results> 10000 mU/mg
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Unit Definition1 U = digestion of 1 µmole of Z-Phe-Arg-AFC substrate (K142-100) per minute at 37°C in 50 mM Sodium Acetate, 100 mM NaCl, pH 5.5
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Molecular Weight24.2 kDa (114-333 aa)
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Storage Temp-70°C
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ShippingDry ice
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Shelf Life12 months
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Concentration0.5 mg/ml
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AppearanceLiquid
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Physical form description0.5 mg/ml in 25 mM Sodium Acetate, 50 mM NaCl, pH 5.5 containing 50% glycerol
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Background InformationCathepsin L is a lysosomal protease that can be secreted from the cell and is implicated to play a role in protein degradation, arthritis, apoptosis, and cancer.
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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GeneCTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolCTSLP2, CTSL3P, CTSLP3
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Short nameCathepsin L, recombinant
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameCathepsin L, H. sapiens Rec.
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene namecathepsin L pseudogene 2
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Synonyms gene
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Synonyms gene name
- cathepsin L-like 2
- cathepsin L1 pseudogene 2
- cathepsin L pseudogene 5
- cathepsin L-like 5
- cathepsin L1 pseudogene 5
- cathepsin L pseudogene 7
- cathepsin L-like 7
- cathepsin L1 pseudogene 7
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-12-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecathepsin L family member 3, pseudogene
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Synonyms gene
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Synonyms gene name
- cathepsin L family member 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-04-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecathepsin L pseudogene 3
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Synonyms gene
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Synonyms gene name
- cathepsin L-like 3
- cathepsin L1 pseudogene 3
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GenBank acession
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Locus
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Discovery year1993-12-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data