Cathepsin G, Human Neutrophil
#
-
Catalog number4713-100
-
Price:
-
Size100 µg
-
-
SynonymsCathepsin G
-
Alternative_namesCathepsin G, CTSG
-
DescriptionInvolved in connective tissue remodeling at sites of inflammation
-
RecombinantNo
-
SourceHuman Neutrophil
-
Purity by SDS PAGE≥95%
-
AssaySDS-PAGE
-
Activity Specifications test method2 to 4 units per mg protein. One unit of activity is defined as the amount of enzyme that hydrolyzes one micromole of Suc-Ala-Ala-Pro-Phe-pNA (1 mM) per minute at 25°C in 160 mM Tris-HCl, pH 7.4, with 1.6 M NaCl.
-
Molecular Weight23.5 kDa
-
Storage Temp-20°C
-
ShippingGel pack
-
Shelf Life12 months
-
AppearanceLyophilized protein
-
Physical form descriptionSalt- free lyophilized solid
-
Reconstitution InstructionsDeionized H₂O
-
Background InformationCathepsin G is a serine protease secreted by activated neutrophils that play a role in the inflammatory response. This enzyme degrades collagen and proteoglycan and can also cause the release of angiotensin II from angiotensin I or angiotensinogen. It has been implicated in connective tissue diseases such as emphysema and rheumatoid arthritis.
-
HandlingCentrifuge the vial prior to opening.
-
UsageFor Research Use Only! Not to be used in humans
-
GeneCTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.
-
PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Gene target
-
Short nameCathepsin G, Neutrophil
-
SpeciesHuman, Humans
-
Alternative nameCathepsin G, H. sapiens Neutrophil
-