Carfilzomib

  • Catalog number
    2385-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    (S)-4-methyl-N-((S)-1-((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide; PR-171
  • Description
    Carfilzomib (PR-171) is a next generation, irreversible and selective inhibitor of the chymotrypsin-like activity of the proteasome. It displays potent antineoplastic activity.
  • CAS Number
    868540-17-4
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₄₀H₅₇N₅O₇
  • Molecular Weight
    719.91
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (~50 mg/ml)
  • Handling
    Protect from light and moisture
  • Tag Line
    A next generation proteasome inhibitor
  • Storage Condition
    -20 ̊C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    11556711
  • SMILES
    CC(C)CC(C(=O)C1(CO1)C)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(C)C)NC(=O)C(CCC3=CC=CC=C3)NC(=O)CN4CCOCC4
  • InChi
    InChI=1S/C40H57N5O7/c1-27(2)22-32(36(47)40(5)26-52-40)42-39(50)34(24-30-14-10-7-11-15-30)44-38(49)33(23-28(3)4)43-37(48)31(17-16-29-12-8-6-9-13-29)41-35(46)25-45-18-20-51-21-19-45/h6-15,27-28,31-34H,16-26H2,1-5H3,(H,41,46)(H,42,50)(H,43,48)(H,44,49)/t31-,32-,33-,34-,40+/m0/s1
  • InChi Key
    BLMPQMFVWMYDKT-NZTKNTHTSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Carfilzomib
  • Alternative name
    Carfilzomib
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