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Alternative_name
α-Carboxybenzylpenicillin disodium salt
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Description
Carbenicillin disodium is a member of the carboxypenicillin β-lactam antibiotic family. Inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Unlike most β-lactams, carbenicillin disodium is limited to primarily gram negative bacteria including Pseudomonas aeruginosa and common enteric species. Carbenicillin is routinely used to select for mammalian cells containing the pET28 resistance plasmid in the Rosetta 2 cell line at an effective concentration of 50 µg/ml.
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CAS Number
4800-94-6
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₁₇H₁₆N₂Na₂O₆S
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Molecular Weight
422.36
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Cell Permeable
No
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Solubilities
H₂O (~50 mg/ml)
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Handling
Protect from air and moisture
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Tag Line
A β-lactam antibiotic and useful selective agent
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
24 months
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MDL Number
MFCD00077683
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PubChem CID
20933
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SMILES
CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)C(=O)[O-])C(=O)[O-])C.[Na+].[Na+]
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InChi
InChI=1S/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/q;2*+1/p-2/t9?,10-,11+,14-;;/m1../s1
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InChi Key
RTYJTGSCYUUYAL-YCAHSCEMSA-L
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MSDS Available
Yes