BT-13

• Catalog number
  B2576-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  BT13, N,N-Diethyl-3-[4-[4-fluoro-2-(trifluoromethyl)benzoyl]-1-piperazinyl]-4-methoxybenzenesulfonamide
• Description
  BT-13 is a potent and selective agonist of RET tyrosine kinase and its downstream signaling cascades. BT-13 promotes neurite growth from sensory neurons in vitro and attenuates experimental neuropathy in the Rat.
• CAS Number
  924537-98-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₃H₂₇F₄N₃O₄S
• Molecular Weight
  517.54
• Cell Permeable
  True
• Purity
  ≥98% by HPLC
• Solubilities
  >20 mg/ml in DMSO
• Handling
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Tag Line
  A potent RET agonist
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• PubChem CID
  46088379
• PubChem CID Link
• SMILES
  CCN(CC)S(=O)(=O)C1=CC(=C(C=C1)OC)N2CCN(CC2)C(=O)C3=C(C=C(C=C3)F)C(F)(F)F
• InChi
  InChI=1S/C23H27F4N3O4S/c1-4-30(5-2)35(32,33)17-7-9-21(34-3)20(15-17)28-10-12-29(13-11-28)22(31)18-8-6-16(24)14-19(18)23(25,26)27/h6-9,14-15H,4-5,10-13H2,1-3H3
• Data Sheet Link
• MSDS Available
  True

• Gene target
  BT-13  
• Gene symbol
  PIRC58, SNORD115-13, SNORD114-13, BTN1A1, IGHV3OR16-13, IGLV3-13, ERVK-13, SNORD116-13, IGHV3-13, IGKV1D-13
• Short name
  BT-13
• Alternative name
  BT-13

Gene info

• Identity
  HGNC:37562
• Gene
  PIRC58
• Long gene name
  piwi-interacting RNA cluster 58
• Locus
  13
• Discovery year
  2009-11-05
• Entrez gene record
  100313918
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:33032
• Gene
  SNORD115-13
• Long gene name
  small nucleolar RNA, C/D box 115-13
• Synonyms
  • HBII-52-13
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033450
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003305.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33001
• Gene
  SNORD114-13
• Long gene name
  small nucleolar RNA, C/D box 114-13
• Synonyms
  • 14q(II-13)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767591
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003206.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:1135
• Gene
  BTN1A1
• Long gene name
  butyrophilin subfamily 1 member A1
• Synonyms gene
  • BTN
• Synonyms gene name
  • butyrophilin, subfamily 1, member A1
• Synonyms
  • BT
  • BTN1
• GenBank acession
  • U39576
• Locus
  6p22.2
• Discovery year
  1995-07-11
• Entrez gene record
  696
• Pubmed identfication
  • 8114113
  • 9382921
• RefSeq identity
  • NM_001732
• Classification
  • Butyrophilins
  • C2-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000016358

Gene info

• Identity
  HGNC:5637
• Gene
  IGHV3OR16-13
• Long gene name
  immunoglobulin heavy variable 3/OR16-13 (non-functional)
• Synonyms gene name
  • immunoglobulin heavy variable 3/OR16-13
• Synonyms
  • IGHV3/OR16-13
• GenBank acession
  • Z29610
• Locus
  16p11.2
• Discovery year
  2000-04-17
• Entrez gene record
  100287372
• RefSeq identity
  • NG_011771
• Classification
  • Immunoglobulin heavy (IGH) orphons
• VEGA ID
  OTTHUMG00000176357

Gene info

• Identity
  HGNC:5899
• Gene
  IGLV3-13
• Long gene name
  immunoglobulin lambda variable 3-13 (pseudogene)
• Synonyms gene name
  • immunoglobulin lambda variable 3-13
  • immunoglobulin lambda variable 3-13 pseudogene
• GenBank acession
  • X97463
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28801
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151215

Gene info

• Identity
  HGNC:39008
• Gene
  ERVK-13
• Long gene name
  endogenous retrovirus group K member 13
• Synonyms gene name
  • endogenous retrovirus group K, member 13
• Synonyms
  • c3_D
• GenBank acession
  • FN806832
• Locus
  3q24
• Discovery year
  2011-05-05
• Pubmed identfication
  • 18664271
  • 21542922

Gene info

• Identity
  HGNC:33079
• Gene
  SNORD116-13
• Long gene name
  small nucleolar RNA, C/D box 116-13
• Synonyms
  • HBII-85-13
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033425
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003328
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5581
• Gene
  IGHV3-13
• Long gene name
  immunoglobulin heavy variable 3-13
• GenBank acession
  • X92217
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28449
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152295

Gene info

• Identity
  HGNC:5747
• Gene
  IGKV1D-13
• Long gene name
  immunoglobulin kappa variable 1D-13
• GenBank acession
  • X17262
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28902
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000188271

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