BQCA

• Catalog number
  B2265-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, Benzyl quinolone carboxylic acid
• Description
  BQCA is a potent M1 muscarinic acetylcholine receptor (mAChR) positive allosteric modulator with selectivity for M1 over M2-M5. The effective range for potentiation of M1 in cells by BQCA is 0.1 to 100 μM with an inflection point value of 845 nM when 3 nM acetylcholine is used. BQCA displays no potentiation, agonism, or antagonism at other mAChRs at concentrations up to 100 μM.
• CAS Number
  338747-41-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₈H₁₅NO₄
• Molecular Weight
  309.32
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~10 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent M1 muscarinic acetylcholine receptor (mAChR) positive allosteric modulator
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD01315710
• PubChem CID
  1476756
• PubChem CID Link
• SMILES
  COC1=CC=C(C=C1)CN2C=C(C(=O)C3=CC=CC=C32)C(=O)O
• InChi
  InChI=1S/C18H15NO4/c1-23-13-8-6-12(7-9-13)10-19-11-15(18(21)22)17(20)14-4-2-3-5-16(14)19/h2-9,11H,10H2,1H3,(H,21,22)
• InChi Key
  BZBBTGCKPRSPGF-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  YES

• Gene target
  BQCA  
• Short name
  BQCA
• Alternative name
  BQCA

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