Bnip3L/Nix Antibody

• Catalog number
  3205-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  Bnip3L/Nix
• Target Alternative Name
  BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like; NIP3-like protein X
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 80 of human Bnip3L.
• Accession
  O60238
• Gene Id
  665
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) affinity purified rabbit anti-Bnip3L polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 1% BSA, 0.02% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot, Immunohistochemistry
• Application And Usages
  The antibody can be used for Western blot analysis (0.5-2 µg/ml) and immunohistochemistry (2-10 µg/ml). The optimal conditions should be determined individually. Other applications have not been tested.
• Description
  Members of Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3α, and Nix (for Nip3-like protein X). Bnip3L/Bnip3α/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. Bnip3L interacts with and overcomes supression by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria. The message RNA of Bnip3L and Bnip3 form a new subfamily of the proapoptotic mitochondrial proteins.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Bnip3L/Nix  
• Gene symbol
  BNIP3L
• Short name
  Bnip3L/Nix Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  B-cellular CLL/lymphoma 2/adenovirus E1B 19kDa interacting protein 3-like/Nix (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  BCL2/adenovirus E1B 19kDa interacting protein 3-like, BNIP3a and NIX, BNIP3L and IDBG-13074 and ENSG00000104765 and 665, protein heterodimerization activity, nuclei, Bnip3l and IDBG-175760 and ENSMUSG00000022051 and 100043324,102641641,12177, BNIP3L and IDBG-635626 and ENSBTAG00000021307 and 534615

Gene info

• Identity
  HGNC:1085
• Gene
  BNIP3L
• Long gene name
  BCL2 interacting protein 3 like
• Synonyms gene name
  • BCL2/adenovirus E1B 19kDa interacting protein 3 like
• Synonyms
  • Nix
  • BNIP3a
• Synonyms name
  • NIP-3-like protein X
• GenBank acession
  • AB004788
• Locus
  8p21.2
• Discovery year
  1997-07-01
• Entrez gene record
  665
• Pubmed identfication
  • 9523198
  • 9973195
• RefSeq identity
  • NM_004331
• VEGA ID
  OTTHUMG00000099433

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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