BIX 01294
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Catalog number1678-5
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PricePlease ask
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Size5 mg
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Alternative_name2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine
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DescriptionSelectively impairs the G9a histone lysine methyltransferase (HMTase) and the generation of H3K9me2 in vitro. BIX-01294 enables neural progenitor cells (NPCs) to be reprogrammed in the absence of exogenous Oct4.
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CAS Number935693-62-2
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₈H₃₈N₆O₂
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Molecular Weight490.65
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Cell PermeableYes
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Purity≥95% by HPLC
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SolubilitiesDMSO (10 mg/ml) or Ethanol (10 mg/ml)
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HandlingProtect from air and moisture
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Tag LineA G9a histone lysine methyltransferase (HMTase) inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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MDL NumberMFCD14560563
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PubChem CID25150857
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SMILESCN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)CC5=CC=CC=C5)OC)OC
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InChiInChI=1S/C28H38N6O2/c1-32-12-7-13-34(17-16-32)28-30-24-19-26(36-3)25(35-2)18-23(24)27(31-28)29-22-10-14-33(15-11-22)20-21-8-5-4-6-9-21/h4-6,8-9,18-19,22H,7,10-17,20H2,1-3H3,(H,29,30,31)
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InChi KeyOSXFATOLZGZLSK-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameBIX 01294
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Alternative nameBIX 01294
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