BI-78D3

• Catalog number
  B1686-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  BI-78D3; BI78D3; BI 78D3; 4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-((5-nitrothiazol-2-yl)thio)-4H-1,2,4-triazol-3-ol; 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-1H-1,2,4-triazol-5-one
• Description
  BI 78D3 is a competitive c-Jun N-terminal kinase (JNK) inhibitor with IC50 of 280 nM that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K.
• CAS Number
  883065-90-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₃H₉N₅O₅S₂
• Molecular Weight
  379.37
• Cell Permeable
  Yes
• Purity
  >98%
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A competitive JNK inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD01313575
• PubChem CID
  2747117
• PubChem CID Link
• SMILES
  C1COC2=C(O1)C=CC(=C2)N3C(=O)NN=C3SC4=NC=C(S4)[N+](=O)[O-]
• InChi
  InChI=1S/C13H9N5O5S2/c19-11-15-16-12(25-13-14-6-10(24-13)18(20)21)17(11)7-1-2-8-9(5-7)23-4-3-22-8/h1-2,5-6H,3-4H2,(H,15,19)
• InChi Key
  QFRLDZGQEZCCJZ-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  BI-78D3  
• Gene symbol
  TMBIM6, SCARB1
• Short name
  BI-78D3
• Alternative name
  BI-78D3

Gene info

• Identity
  HGNC:11723
• Gene
  TMBIM6
• Long gene name
  transmembrane BAX inhibitor motif containing 6
• Synonyms gene
  • TEGT
• Synonyms gene name
  • testis enhanced gene transcript
• Synonyms
  • BI-1
  • BAXI1
• Synonyms name
  • BAX inhibitor 1
• GenBank acession
  • X75861
• Locus
  12q13.12
• Discovery year
  1994-08-30
• Entrez gene record
  7009
• Pubmed identfication
  • 8530040
  • 9660918
• RefSeq identity
  • NM_003217
• Classification
  • Transmembrane BAX inhibitor motif containing
• VEGA ID
  OTTHUMG00000169652

Gene info

• Identity
  HGNC:1664
• Gene
  SCARB1
• Long gene name
  scavenger receptor class B member 1
• Synonyms gene
  • CD36L1
• Synonyms gene name
  • CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1
  • scavenger receptor class B, member 1
• Synonyms
  • SRB1
  • CLA-1
  • CLA1
  • SR-BI
• GenBank acession
  • Z22555
• Locus
  12q24.31
• Discovery year
  1994-09-06
• Entrez gene record
  949
• Pubmed identfication
  • 7689561
• RefSeq identity
  • NM_005505
• Classification
  • Scavenger receptors
• VEGA ID
  OTTHUMG00000168544

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