BEZ235 (NVP-BEZ235)
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Catalog number1626-25
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PricePlease ask
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Size25 mg
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Alternative_nameNVP-BEZ235
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DescriptionOrally active PI-3 kinase inhibitor; Dual PI3K/mTOR inhibition; BEZ235 showed high target specificity and demonstrated anti-proliferative activity against tumor cell lines in animal models of cancer.
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CAS Number915019-65-7
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₃₀H₂₃N₅O
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Molecular Weight469.55
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Cell PermeableYes
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Purity≥99% by HPLC
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SolubilitiesDMSO (10 mM)
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HandlingProtect from air and moisture
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Tag LineA PI3 Kinase inhibitor
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Storage Condition-20°C
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Shipping ConditionRT
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Shelf Life24months
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MDL NumberMFCD10565944
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PubChem CID11977753
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SMILESCC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3N(C2=O)C)C5=CC6=CC=CC=C6N=C5
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InChiInChI=1S/C30H23N5O/c1-30(2, 18-31)22-9-11-23(12-10-22)35-28-24-15-19(21-14-20-6-4-5-7-25(20)32-16- 21)8-13-26(24)33-17-27(28)34(3)29(35)36/h4-17H,1-3H3
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InChi KeyJOGKUKXHTYWRGZ-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameBEZ235 (NVP-BEZ235)
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Alternative nameBEZ235 (NVP-BEZ235)
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