Beta3-AR Antibody

  • Catalog number
    3939-200
  • Price
    Please ask
  • Size
    200 µg
  • Antibody Target
    AR-Beta3
  • Target Alternative Name
    Beta-3 AR, beta 3-AR, Beta-3 adrenoceptor, beta3-adrenergic receptor, beta-3 adrenoreceptor
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Rat
  • Immunogen Sequence
    Synthetic peptide surrounding amino acid 405 of rat Beta3-AR
  • Accession
    NP_037240.1
  • Gene Id
    25645
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    0.5 mg/ml
  • Formulation
    200 µg (0.5 mg/ml) affinity purified rabbit anti-Beta3-AR polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
  • Purification
    Affinity purified
  • Application
    Western blot
  • Positive Control
    Rat kidney tissue lysate
  • Application And Usages
    Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually. Rat kidney tissue lysate can be used as a positive control.
  • Description
    The neurotransmitter/hormone adrenaline (epinephrine, adrenalin) plays a central role in the mammalian stress response, increasing heart rate, raising blood pressure, and increasing blood glucose levels. Adrenaline activates both alpha-adrenergic receptors and beta-adrenergic receptors. There are mainly three subtypes of beta adrenergic receptors known, beta1, beta2, and beta3. These receptors are expressed primarily in the heart, respiratory tissue, and adipose tissue. Beta3-receptors are abundant in brown adipocytes and play vital roles in lipolysis and thermoregulation. Beta adrenergic receptors are gaining much interest among researches in the studies of type-2 diabetes mellitus and obesity. It is also being considered as a therapeutic target for heart failure.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • FACS Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    AKR1B1, PRKN, AR, EDNRA
  • Short name
    Beta3-AR Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    Beta3-AR (antibody to-)
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    aldo-keto reductase family 1 member B
  • Synonyms gene
  • Synonyms gene name
    • aldo-keto reductase family 1, member B1 (aldose reductase)
  • Synonyms
  • Synonyms name
  • GenBank acession
  • Locus
  • Discovery year
    1991-08-07
  • Entrez gene record
    231
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Aldo-keto reductases
  • VEGA ID
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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